Antipsychotic Drugs Differ in Efficacy, Tolerability
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چکیده
The FDA is investigating the unexplained deaths of 2 patients who received intramuscular injections of olanzapine pamoate (Zyprexa Relprevv). The patients died 3–4 days after receiving appropriate doses of the drug, and both patients were found to have very high olanzapine blood levels after death. High doses of olanzapine can cause delirium, cardiopulmonary arrest, cardiac arrhythmias, and reduced level of consciousness ranging from sedation to coma.
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